HORDB

ID: hor004404
Uniprot ID: P16224
Protein name: Locustatachykinin-2
Gene name: NA
Organism: Locusta migratoria (Migratory locust)
Family: Tachykinin family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Locusta (genus), Oedipodinae (subfamily), Acrididae (family), Acridoidea (superfamily), Acridomorpha, Acrididea (infraorder), Caelifera (suborder), Orthoptera (order), Polyneoptera (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Function: Myoactive peptide. Stimulates the contraction of the oviduct and foregut.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004404_AF2.pdb

hor004404_ESM.pdb

Mass:	122693	Formula:	C50H75N13O13
Absent amino acids:	CDEHIKMNQTW	Common amino acids:	G
pI:	9.35	Basic residues:	1
Polar residues:	4	Hydrophobic residues:	4
Hydrophobicity:	36	Boman Index:	-283
Half-Life:	4.4 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	78
Instability Index:	5237	Extinction Coefficient cystines:	1490
Absorbance 280nm:	165.56

PubMed ID: 2311766
Title: Locustatachykinin I and II, two novel insect neuropeptides with homology to peptides of the vertebrate tachykinin family.